Born in Prato, Nuti began his professional career as an actor in the late 1970s, when he formed the cabaret group Giancattivi together with Alessandro Benvenuti and Athina Cenci.

The following year Nuti abandoned the trio and began a solo career with three movies directed by Maurizio Ponzi: What a Ghostly Silence There Is Tonight (1982), The Pool Hustlers (1982) and Son contento (1983).

The 1990s were however a period of decline for the Tuscan director, with unsuccessful movies such as OcchioPinocchio (1994), Mr. Fifteen Balls (1998), Io amo Andrea (2000) and Caruso, Zero for Conduct (2001).

On 2 September 2006, just before starting to shoot a new film (which was going to be titled Olga e i fratellastri Billi), Nuti was admitted to the hospital Policlinico Umberto I in Rome, following a severe fall from the stairs of his home.

[1] The accident caused Nuti a subdural hematoma that led to serious cerebral damage, leaving him unable to speak or move.