He came from a family consisting of many figures high in the hierarchy of the Catholic Church and state officials or military commanders of the Republic of Venice.

On 17 December 1635, Francesco Bianchi was appointed during the papacy of Pope Urban VIII as Bishop of Sapë.

[5] Bardhi also wrote a biography of George Kastrioti Skanderbeg, called The Apology of Scanderbeg published in Venice in 1636.

[6] The Apology of Scanderbeg was a polemic against Slavic Catholic priest Ivan Tomko Mrnavić, who claimed that Kastrioti was of Slav origin.

[5] From 1637 on, Bardhi submitted reports in Italian and Latin to the Congregation of the Propaganda Fide in Rome which contain a mine of information about his diocese, about political developments, about Albanian customs and about the structure and position of the Catholic Church in Ottoman-occupied Albania.