Franz Riegel (9 February 1843 – 26 August 1904) was a German internist and gastroenterologist, who was a native of Brückenau.
In 1871, he was a lecturer of experimental pathology at the University of Würzburg, and in 1874, he became director of the Cologne city hospital.
Riegel's research involved studies of the respiratory system, vasomotor influences, the effects of substances such as caffeine, atropine and jaborandi, conditions of the heart and blood pressure in nephritis, et al.
He is remembered for his extensive research of gastric disorders; his last written work discussing distinctions between hyperacidity and hypersecretion.
His best known written work was Die Erkrankungen des Magens (1896), ("Diseases of the stomach"), a book that was later translated into English.