Frederick Louis (German: Friedrich Ludwig; 27 October 1619 – 11 April 1681) was the Duke of Landsberg from 1645 until 1681, and the Count Palatine of Zweibrücken from 1661 until 1681.

After his father's death in 1645, Frederick Louis inherited his territories devastated by the Thirty Years' War.

To a limited extent he contributed to the reconstruction efforts and he promoted trade to stabilise the situation.

With the sons of his first marriage predeceased and the sons of his second morganatic marriage illegitimate, he was succeeded by King Charles XI of Sweden.

Frederick Louis married his first cousin, Juliana Magdalena of Palatinate-Zweibrücken (23 April 1621 - 25 March 1672), daughter of Duke John II, on 14 November 1645 in Düsseldorf and had the following children: Frederick Louis morganatically married Anna Marie Elisabeth Hepp (c. 1635 - 8 March 1722) on 21 August 1672 and had the following children: