The Frederick Stearns Building is a manufacturing plant located at 6533 East Jefferson Avenue in Detroit, Michigan.

[3] Frederick Stearns & Company, established in 1855,[4] was a leading pharmaceutical manufacturer in 19th century Detroit.

[4] It originally contained Stearns's production facilities, as well as warehouses and white-collar offices.

[5] The center pavilion contains an arched stone entryway and a clock on the third floor.

[3] Fourth-floor gables above the end pavilions add to the appeal of the building.