Due to the presence of numerous car companies within it at the turn of the 20th century, Milwaukee Junction is considered the "cradle of the Detroit auto industry".
[2] Ford Motor Company also established a presence in Milwaukee Junction when it opened the Piquette Avenue Plant.
[4] Henry Ford also conducted experiments in assembly line production at the Piquette Avenue Plant, which was used later in Highland Park.
The Conrail North Yard Branch, shared by CSX Transportation and the Norfolk Southern Railway, also crosses the site coming in from the southwest paralleling GTW's Shoreline and Mt.
Trains of Amtrak's Wolverine service pass through the junction six times a day, using the GTW's Shore Line and Holly subdivisions.