In June 2018, Potomac Nationals owner Art Silber announced that he had signed a letter of intent to build a new stadium in Fredericksburg, Virginia, that would open in April 2020.

[11] With the 2020 season start postponed due to the COVID-19 pandemic, the Nationals held a virtual opening day on April 23, 2020.

[21] In March 2020, the team unveiled their new mascot, Gus, described as "fat and fluffy" with purple fur and bright green eyebrows.

[1] The 2020 minor league baseball season was initially postponed, and ultimately cancelled altogether, due to the COVID-19 pandemic.

[27] The Nationals played their first home game at FredNats Ballpark on May 11, 2021, losing to the Delmarva Shorebirds, 7–5, with 2,065 people in attendance.

[28][29] The team finished its inaugural 2021 season with a 44-76 win-loss record, ending in fourth (last) place in the North Division of the Low-A East League.

[35] On September 18, 2024, the FredNats beat the Kannapolis Cannon Ballers, 3-0, at home, in the third game of a 3-game series to win their first Carolina League championship.