Men's sports include baseball, basketball, cross country, golf, lacrosse, soccer, swimming, indoor/outdoor track and field, and tennis.

The women's soccer team made it to the final four in 2006 after winning the ODAC tournament for the first time in program history.

The Virginia Wesleyan College softball team won the 2017 NCAA Division III National Championship with a record 54 wins.

[3] Virginia Wesleyan University added a co-ed club Esports program that offers students the chance to participate in video game competitions at the collegiate level in fall 2019.

[5] Graduate student Hanna Hull and fifth-year senior Jessica Goldyn were named the 2021 Schutt Sports/NFCA Division III Pitcher and Player of the Year respectively after helping lead the team through the Regional and National Tournaments.