Freeze spray

[2] Freeze sprays are also used to contract metal for assembly or disassembly of interference fit parts.

[citation needed] The extreme temperature can cause viscoelastic materials to change to glass phase.

[3] In medical applications, spray cans containing dimethyl ether[4] or tetrafluoroethane may also be used to freeze and destroy tissue, for removal of warts and skin tags, or other uses in cryosurgery.

[5] Chloroethane may be used as a topical pain reliever, and an alternative to ice pack therapy to reduce inflammation and swelling.

Research is continuing to help control the application dosage and time to minimize permanent damage to the animals.