Fresnillo de Trujano is a town and municipality in Oaxaca in south-western Mexico.

The municipality covers an area of 98.24 km².

It is part of the Huajuapan District north of the Mixteca Region.

As of 2005, the municipality had a total population of 852.

[1] This article about a location in the Mexican state of Oaxaca is a stub.