Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.
[3] It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).
[4] The attribution to Galen is disputed,[3] and has variously been attributed to Thomas Sydenham[5] and Rudolf Virchow.
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