Since this platform falls squarely in the center of the worldwide automobile market, GM plans to produce a great many Epsilon vehicles with over a dozen variations.

When the platform debuted, there was talk of an "Epsilon Wide" derivative, which was supposed to have provided the underpinnings for the Buick LaCrosse and Saab 9-5.

However, the program was cancelled and the LaCrosse was put on the W platform, and the 9-5 was given a quick refresh for the 2006 model year.

[citation needed] The Epsilon platform is a midsize front-driver promising a 200 percent improvement in rigidity, with aluminum suspension components—MacPherson struts in front and a four-link independent arrangement in the rear, and four-wheel disc brakes.

In long wheelbase format, Epsilon II supports US EPA Large Cars, allowing GM to replace the G and W platforms.