[1] After some hostilities with the conservative cabinet, he was accused of taking part in a conspiracy against Pedro Santana, who subjected him, as well as his brother, José Joaquín Puello, to persecution and subsequent execution in December 1847.
[3] During the years of the Unification of Hispaniola, a decree issued by the then governor of the island, Jérôme-Maximilien Borgella, enforced mandatory military service of young Dominicans of fighting age.
Together with his brothers, José Joaquín and Eusebio they became interested in the separatist movement led by Juan Pablo Duarte, who had founded the secret society La Trinitaria in 1838.
[6] He was Commander of Arms of Samaná for some time, while in those functions he was accused along with his brother José Joaquín Puello of complicity in a conspiracy against the government.
In 1916, his remains were exhumed and finally exalted in the National Pantheon, where he is buried alongside other prominent figures of the Dominican Republic.