She is a faculty member of the Walter and Eliza Hall Institute of Medical Research, within the Molecular Immunology division.

Her research has focused on understanding the signals that drive the initial development of protective immunity against pathogen infections, such as influenza and herpes viruses.

Following her PhD, she took up a Postdoctoral Fellowship in viral immunology with Nobel Laureate Professor Peter Doherty at St Jude Children's Research Hospital in Memphis, USA.

Belz was Editor-of-Chief of Immunology and Cell Biology until 2016, and was subsequently a Deputy Editor of the journal for several years.

[3] In 2008, Belz was awarded the Gottschalk Medal by the Australian Academy of Science for her contribution to a series of pioneering discoveries illuminating how the immune system deals with viruses.