Gaetano Casati (4 September 1838 – 7 March 1902) was an Italian explorer of Africa, born in Lesmo, at that time in the Austrian Empire.

After studying at the Academy in Pavia he entered the Italian army in 1859 and served there until 1879.

On December 24, 1879, he sailed for Africa under commission of the Società d'Esplorazione Commerciale d'Africa.

Subsequently, he lived in the Kingdom of Kabba Rega, was condemned to death by the monarch, but escaped to Lake Albert, where Emin Pasha rescued him in 1888.

In December 1889, Casati reached the coast with Emin Pasha and Stanley.