Gantenerumab is a monoclonal antibody for the treatment of Alzheimer's disease being developed by Hoffmann-La Roche pharmaceuticals.

[1][2] Gantenerumab binds to and clears aggregated beta amyloid fibers.

[3] A phase III clinical trial of gantenerumab was stopped early because of a lack of efficacy.

[4] Gantenerumab was also evaluated in younger patients at high risk of developing Alzheimer's disease[5] but after five years of treatment, the drug did little to slow cognitive decline in patients.

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