[2] Calgary Trail and Gateway Boulevard enter Edmonton from the south along Highway 2, the city's busiest entrance.

[5] The freeway continues north past Gateway Park, a rest area which is marked by the historic Leduc No.

Gateway Boulevard and 104 Street pass through mixed light industrial and commercial areas before entering Old Strathcona and intersects Whyte (82) Avenue.

[12] The freeway proposal through the North Saskatchewan River valley and its feeder ravines proved to be very controversial, with public protests suspending construction.

[17][18] Highway 2 used to enter Edmonton and abruptly transitioned from a freeway to an arterial roadway with traffic signals at Ellerslie Road and 23 Avenue; however the intersections were upgraded when interchanges were completed in 2001 and 2011 respectively.

There have been proposals to improve the Gateway Boulevard connection with the Walterdale Bridge and downtown Edmonton by removing a hairpin turn required to access Queen Elizabeth Park Road.

Due to the topography of the river valley, proposals have shown that Gateway Boulevard would have to be realigned in pass under Saskatchewan Drive.

List of neighbourhoods Calgary Trail and Gateway Boulevard run through, in order from south to north.