Founded by Mike Wilson and associates in January 1998 and originally based in Dallas, the company was acquired by Take-Two Interactive in May 2000.

In August 2001, Take-Two Interactive closed Gathering of Developers' Dallas headquarters and moved the label in-house, to New York City.

[2] Wilson's stated vision for the company was to have a video games publisher run by experienced developers rather than marketeers and conventional businessmen.

[7] Other founding partners included Edge of Reality, 3D Realms, Epic Games, PopTop Software, and Ritual Entertainment.

[24][25] Following the departure of On Deck Interactive's CEO Robert Westmoreland, the label was shut down again on March 5, 2001, with all of its upcoming games shifted to Gathering of Developers.

[27][28] In his honor, Gathering of Developers announced the "Doug Myres Substance Award" in June that year, which would be handed out at the July 2001 edition of the Cyberathlete Professional League, with a donation to the Dallas Children's Advocacy Center made in the recipient's name.