Genome Project–Write

[1][2][3][4][5][6] Formally announced on 2 June 2016, the project leverages two decades of work on synthetic biology and artificial gene synthesis.

The newly created GP-Write project will be managed by the Center of Excellence for Engineering Biology,[7] an American nonprofit organization.

Researchers expect that the ability to artificially synthesize large portions of many genomes will result in many scientific and medical advances.

The GP-Write CAD will automate workflows to enable collaborative efforts critical for scale-up from designing plasmids to megabases across entire genomes.

Among the many goals of GP-Write are the making of cell lines resistant to all viruses and synthesis assembly lines to test variants of unknown significance that arise in research and diagnostic sequencing of human genomes (which has been exponentially improving in cost, quality, and interpretation).

Since the Human Genome Project first sequenced the human genome from 1987 to 2004 at a cost of US$3 billion, costs have fallen precipitously, outpacing even Moore's law , and were ≈US$1,000 in 2015. More widely available genome sequencing has led to more data on variants of uncertain significance.