George Brouse (1790 – February 12, 1860) was a farmer, businessperson, and political figure in Upper Canada.

He was born in Matilda Township, Dundas County, Upper Canada, in 1790, the son of Peter Brouse, a United Empire Loyalist from Stone Arabia, Montgomery County, New York.

A small community originally known as Matilda and later Iroquois, Ontario, developed in the area.

In 1810 Peter Brouse had converted George and his brother Peter to Methodism but he did not continue in this faith until the great revival in 1822, when he was restored, and became a lifelong steward of the church.

During the 1820s, he built a gristmill, sawmill, shingle factory, and woollen mill.