Wyld became interested in homeopathy in 1851 after discovering the work of Samuel Hahnemann whilst a medical student at Edinburgh.

After he obtained his M. D. with the thesis 'The liver: the hydrogenator in animals' [1] he moved to London where he taught homeopathy and in 1876 became president of the British Homeopathic Society.

[2] Wyld was a vice-president for the British National Association of Spiritualists and an early member of the Society for Psychical Research.

[7] Wyld initially was impressed by Blavatsky, believing her to possess mediumistic powers, but later fell out with her.

He resigned after she had written an article in The Theosophist claiming "there is no personal or impersonal God."