Zariphis met Sultan Abdul Hamid II when the latter was a shahzade with a low expectation of ascending to the throne.

The prince, having financial troubles, called on the expertise of Zariphis to manage his personal wealth.

After Abdul Hamid II became sultan, he continued to utilize Zarifi's advisory services during the First Constitutional Era.

One of the buildings of the Balıklı Greek Hospital is named Zariphion in his honor, not because of a specific bequest but in remembrance of the many at-large donations he gave during his lifetime.

Georgios Zariphis's summertime mansion, Zarifi Köşkü,[1] in the Yeniköy district, is a listed and protected historical building, which in 2005 started undergoing renovation as the headquarters of the Turkish Football Federation.