[1] He and his American-born wife settled in Denver, in the hope that the mountain air would prove beneficial to the tuberculosis with which she had been diagnosed.
[2] Webb's wife finally succumbed to her tuberculosis, dying in 1903, and he himself suffered a near-fatal bout of sepsis leading him to return to Europe to further his medical education.
When he returned to the United States in 1907, he opened a specialized practice limited to the research and treatment of tuberculosis.
During the war, he spent much of his time in France, performing clinical examinations as well as lectures and other educational programs.
[3] In 1924, Webb founded the Colorado Foundation for Research in Tuberculosis, which was renamed in his honor following his death.