Gigactonine is a naturally occurring diterpene alkaloid first isolated from Aconitum gigas.

Although a novel structure at that time, it was recognised to be related to known diterpene alkaloids including delsoline, which is methylated on its 4-hydroxymethyl primary alcohol sidechain.

Similarly, their full biosynthetic pathway is only known in outline in most cases.

[2] Gigactonine has been reported as the main alkaloid in the flowers of Aconitum lycoctonum[3] and has been isolated from Delphinium[4] including Delphinium ajacis[5] and other Consolida species in the Ranunculaceae plant family.

[6] Compounds related to aconitine are widely studied for their properties in biological systems and these have been reviewed.