She showed interest in the arts from an early age and started dancing at the Ita Medina Academy when she was 15 years old.
Her third album, Quiero Estar Contigo, was equally successful reaching the top places on the Billboard charts.
The album featured a version of Juan Gabriel's song Perdóname, olvídalo in a duet with Dominican Sergio Vargas which was very successful.
Recently, she appeared in the play La Verdadera Historia de Pedro Navaja, with Gilberto Santa Rosa and Yolandita Monge.
In 2007, Gisselle was invited to host the morning radio show El Bayú de la Mañana at SalSoul.
Gisselle also has a brother named Miguel A Ortiz Caceres and lives in Hartford, CT. After her divorce she has had relationships with model and actor Julian Gil, and baseball player Roberto Alomar.