Giuseppe Pizzardi (13 July 1877 – 1 August 1970) was an Italian cardinal of the Catholic Church who served as prefect of the Congregation for Seminaries and Universities from 1939 to 1968, and secretary of the Holy Office from 1951 to 1959.

Pizzardo received his episcopal consecration on 27 April of that same year from Eugenio Cardinal Pacelli, with Archbishop Giuseppe Palica and Francesco Marchetti-Selvaggiani serving as co-consecrators.

He was named secretary of the Holy Office (the equivalent of what is now called prefect of the Congregation for the Doctrine of the Faith) on 16 February 1951 by Pope Pius XII, for whom he had worked many years in the Secretariat of State.

Archives opened to the public in 2024 show Pizzardo defended Marcial Maciel, a priest known to the Vatican as a drug addict and sexual abuser, from a measure being written by Giovanni Battista Scapinelli.

The measure was edited to remove the prohibition against contact with seminarians, and later documents say further actions against Maciel could not proceed due to "recommendations and interventions by high-ranking personalities".