The source is located south of the town of Cumnock, through which it flows.

Close to the source there is the Carsgailoch Martyrs Monument marking the spot where three covenanters were shot by government troops in 1685.

[1] The stream flows north towards the town of Cumnock, collecting an outflow from the Black Loch, passing Glaisnock House[2] then crossing under the A76, entering Cumnock's Caponacre industrial estate and skirting Murray Park where it is joined by the Holm Burn which rises on the north-west flank of Avisyard Hill.

The river then makes its way under the Glaisnock Viaduct towards Cumnock before finally joining the Lugar Water near the town centre.

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