Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication.

[1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas.

Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl.

It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.

[2] This drug article relating to the gastrointestinal system is a stub.