Glottiphyllum regium is a rare species of succulent plant, in the family Aizoaceae.

It is restricted to a small arid area near Calitzdorp in the Western Cape, South Africa.

The leaves are bright green, upturned, fleshy and are born in pairs.

The two leaves in a leaf-pair are a very similar size, unlike many other species of Glottiphyllum.

The leaf also does not have a swollen base (unlike Glottiphyllum cruciatum).