Glutelins are a class of prolamin proteins found in the endosperm of certain seeds of the grass family.
Glutelins are the primary protein form of energy storage in the endosperm of rice grains.
[2] This class was originally differentiated from prolamins by Thomas Burr Osborne according to its low solubility.
[3] There are typically both high-molecular-weight (HMW) and low-molecular-weight (LMW) glutelins in most grass species.
Individuals possessing the HLA-DQ8 class II antigen receptor gene may demonstrate increased reactivity to high-molecular weight glutenin (as measured by increased levels of pro-inflammatory cytokine interferon gamma), though such observations are limited to one patient.