Glycymeris americana, or the American bittersweet, is a species of bivalve mollusc in the family Glycymerididae.

It can be found along the Atlantic coast of North America, ranging from Virginia to Texas and Brazil.

It is a sturdy shell, nearly circular in outline and rather flattened and has mottled brown markings on a white background.

It has low, rounded ribs and the annual growth rings can be seen.

The margin is slightly serrated and there is no pallial sinus.