European settlement began in 1800 when Tomás Garcia, from Minas Gerais, took possession of a vast area of land called Campo Limpo.

At the beginning of the twentieth century the railroad arrived and a town grew around the station.

Campo Limpo became a district of Catalão in 1913, later separating to become a municipality in 1931 and changing the name to Goiandira, after the name of the railroad station.

The economy is based on cattle raising for meat and milk, in addition to agriculture—mainly corn and soybeans.

The main ones were rice, bananas, sugarcane, beans, manioc, corn, and soybeans.