[1] The hospital was built on a greenfield site adjacent to Griffith University’s Gold Coast campus at a cost of approximately A$1.8 billion.

The hospital has seven main buildings, with a total floor space of approximately 170,000 m2 (1,800,000 sq ft) (excluding car parks).

In early 2023, the Queensland Government announced that $72 million would be invested into the Gold Coast University Hospital sub-acute expansion project.

This project would bring three new wards to provide 70 extra sub-acute beds to care for patients with complex behavioural issues.

The G:link light rail system runs from Helensvale railway station to Broadbeach South via the Southport CBD and Surfers Paradise.