The Grapevine Mountains is a mountain range located along the border of Inyo County, California and Nye County, Nevada in the United States.

The mountain range is about 22 miles (35 km) long and lies in a northwest-southeasterly direction along the Nevada-California state line.

The range reaches an elevation of 8,738 feet (2,663 m) at Grapevine Peak, near Phinney Canyon on the Nevada side.

Most of the Grapevine Mountain chain is in Death Valley National Park.

The range was named for the wild grapes in the area.