Gratini (Greek: Γρατινή) is a village of Rhodope regional unit in northern Greece, 13 km north of Komotini.

[3] The village first appears in the late Byzantine era, as the town of Gratzianous (η Γρατζιανούς), while Ottoman documents mention it as Iğrican and Ağricanhišar.

[4] The late medieval village may possibly be identical to the ancient city of Gratianopolis, named after Emperor Gratian (r. 367–383), whose bishop is recorded as taking part in the First Council of Ephesus in 431.

In 1344, during the war of 1341–1347, the well-fortified town was captured by John VI Kantakouzenos (r. 1341–1354), who appointed his son Matthew to rule over it and the surrounding province.

Gratzianous remained the seat of Matthew and his family until 1355/56, when, after another civil war, he surrendered it and all his Thracian domains to John V Palaiologos (r. 1341–1391) in exchange for the Despotate of the Morea.