The Great Brak River (Afrikaans: Groot-Brakrivier) is a river in the Western Cape, South Africa.

The mouth of the river lies at the town of Great Brak River which falls under the Mossel Bay Municipality.

[2] The nearest towns are Mossel Bay, 24 km to the west, and the largest town in the southern Cape George, 34 km to the east by road.

In 1734 Jan de la Fontaine, Governor of the Cape Province, claimed Mossel Bay for the Dutch East India Company and the Great Brak River was proclaimed the eastern boundary of the Cape.

This article related to a river in South Africa is a stub.