Great Crossing is an unincorporated community located in Scott County, Kentucky, United States.

Great Crossing is located in west-central Scott County at 38°12'56.1"N 84°36'21.1"W and is part of the Lexington-Fayette metropolitan area.

Elkhorn Creek, an 18 mile long navigable waterway, bisects the community.

The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

The location was centered around a shallow area where bison had crossed the Elkhorn Creek.