At launch, it operated a Eurocopter EC135, but as flying hours increased the funding was not available, so the charity moved to a MBB Bo 105 helicopter.

On 1 August 2017, GWAAC upgraded to an EC135 T2+ model, registration G-GWAC, leased from Babcock Mission Critical Services Onshore, which has more advanced features and a longer range.

[5] A site was identified in South Gloucestershire, adjacent to the Almondsbury M4/M5 Interchange,[6] approximately 2 miles (3.2 km) north of the Filton base.

[8] In July 2018, GWAAC launched a public appeal to raise funds to buy the new airbase from BAE Systems,[9] following it being put up for sale during its construction.

The specialist critical care team consists of a paramedic and doctor, who provide a remote emergency department to the patient.

[18] During the COVID-19 pandemic the service responded to COVID-19 cases, and crew members joined a team carrying out inter-hospital transfers for COVID-19 patients requiring intensive care.