It is one of 18 communities that form the basis of the Fox Cities, the third largest metropolitan area in Wisconsin.

The former unincorporated community of Greenville and the ghost town of Wakefield are located in the village.

Many of the village's largest employers are located in business parks surrounding the airport.

Air Wisconsin, the largest privately owned regional airline in the country, is headquartered in Greenville.

[6][7] Other businesses include School Specialty, the village's largest employer; Amazon; Federal Express; Gulfstream Aerospace; VF Corporation; Miller Electric; Plexus; Oshkosh Corporation; Badger Plug; Valley Bakers Cooperative; Sonoco Products; Asten Johnson; and Zebra Technologies.

The Village maintains approximately 210 acres (0.85 km2) of parkland at 10 facilities located throughout the community.

These include: The Wisconsin Department of Natural Resources-managed Heath Van Handel Memorial Forest is located in Greenville.

The 39-acre forest was previously a nursery, test area, and arboretum for the Institute of Paper Chemistry.