Situated beside Moosehead Lake, Greenville is drained by Wilson Stream.

As of the census[4] of 2000, there were 1,319 people, 606 households, and 346 families residing in the CDP.

There were 905 housing units at an average density of 215.7 per square mile (83.3/km2).

The racial makeup of the CDP was 98.56% White, 0.15% Black or African American, 0.30% Native American, 0.30% Asian, 0.08% from other races, and 0.61% from two or more races.

38.1% of all households were made up of individuals, and 23.1% had someone living alone who was 65 years of age or older.