[4] In 2000, at the age of 25, Selkoe founded Karmaloop from his parents' basement in Jamaica Plain while working as an urban planner with the Boston Redevelopment Authority.
For his work with Karmaloop, Selkoe received the Ernst & Young Entrepreneur Of The Year 2012 Award in the e-commerce category in New England.
[7] In June 2015, Greg partnered with Paul Judge and Cedric Rogers to create Curateurs,[8] a website devoted to exclusive men’s fashion items.
[10] Under Selkoe's leadership, XSET expanded into multiple esports titles, including Fortnite, Rocket League, Call of Duty, and Apex Legends.
[11] Some of XSET's notable moves include acquiring Queens Gaming Collective in 2023,[12] signing professional Fortnite player and Twitch streamer with over 7.5+ million subscribers as of May 2024, Cody "Clix" Conrod,[13] popular content creators like Kris London and CashNasty,[14] and securing investments from entities like Quality Control Music[15] and several NFL players.