Grizano (Greek: Γριζάνο) is a village in the Trikala regional unit, Greece, part of the Farkadona municipality.

Grizano is located on the edge of the Thessalian Plain, 4 km (2.5 mi) north of Farkadona town, and 25 km (16 mi) east of the city of Trikala.

One of the largest inland castles built in Greece is the castle of Grizano, that is located on a hill north east of the village.

The castle was built during the Middle Ages but the exact date is unknown.

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