Players control the luchador Juan and explore an open, non-linear world to complete the central story objectives while collecting necessary character upgrades and battling enemies.

The game features drop-in co-op play, with the second player assuming the role of Tostada, Guardian of the Mask.

On the Dia de los Muertos (Day of the Dead), he goes into town to meet with his childhood friend and love interest, El Presidente's daughter, Lupita.

An evil charro skeleton named Carlos Calaca attacks the village and kidnaps her from el Presidente's Mansion.

She gives Juan a mystical mask that transforms him into a powerful luchador and brings him back to the world of the living.

The game then follows Juan's battle to rescue his beloved and to stop Calaca's plan to sacrifice her in a ritual that would unite the worlds of living and dead under his rule.

Juan pursues Calaca to the altar where the ceremony is being held and defeats him, but does not arrive in time to save Lupita.

In the normal ending, Juan returns to his village and lives his life in peace until reuniting with Lupita in the afterlife and the mask disappears.

In the true ending, attained if the player clears all the hidden trials, Lupita is revived by the power of Juan's mask which breaks apart, and the two return together to the village where they get married.

Lastly, identity swap switches the costumes of Juan and Tostada and makes attacks stronger and throws weaker.

Each of the new character outfits requires a certain number of medals to unlock and grants new abilities while being worn by Juan or Tostada.

Gamespot rated the DLC 7.5/10 and said "El Diablo's Domain is a solid addition to an already great game that will make you laugh and push you to your limits, for better or worse.

[20] In July 2015, DrinkBox Studios teamed with the subscription box company, IndieBox, to distribute an exclusive, custom-designed, individually-numbered physical release of Guacamelee!

This limited collector's box includes a flash-drive with a DRM-free game file, official soundtrack, instruction manual, Steam key, and various custom-made collectibles.