The Gulf of Argostoli (Greek: Κόλπος Αργοστολίου) is a gulf of the Ionian Sea on the island of Cephalonia, western Greece.
It separates the Paliki peninsula from mainland Cephalonia, and opens toward the Ionian Sea in the south.
Lixouri, the second-largest town of Cephalonia, is situated on its western shore, and the capital Argostoli is situated on a bay in the eastern shore.
The main settlements on the shore of the gulf are, from the southwest and clockwise: Lixouri, Agios Dimitrios, Kouvalata, Kontogourata, Farsa, Drapano and Argostoli.
Concerns have risen about the environmental effects of fish farming in the gulf.