Gympie Road is lined with many shops, fast food outlets, restaurants, car yards, factories, motels, caravan parks, parks and schools including: The first private land sale occurred on Gympie Road near Kedron Brook in 1857.

Farms, slaughter yards[2] and tanneries[3] were common sights along Gympie Road prior to World War I.

The tram line from the Brisbane CBD was extended to Kedron Park Hotel in 1914, Lutwyche Cemetery in 1925 and Chermside in 1947.

This proposal would use and rename Gympie Road for the northward part of the route and then extend it eastwards towards Redcliffe.

Translink is planning for a new section of the Northern Busway from Kedron to Bracken Ridge that will generally follow Gympie Road.