As an aerosol propellant, HFC-227ea is used in pharmaceutical metered dose inhalers such as those used for dispensing asthma medication.
The decomposition produces a sharp, pungent odour, which can be perceived in concentrations far below a dangerous level.
Prior to re-entry of a room where HFC-227ea system has been activated to suppress a fire, the atmosphere should be tested.
An Acid Scavenging Additive added to heptafluoropropane reduces the amount of hydrogen fluoride.
[3] Due to its high GWP, the HFC-227ea has been included in the list of controlled substances of the Montreal Protocol (2016 Kigali amendment, in effect in January 2019).