HMS Oxford was a 54-gun fourth-rate ship of the line of the Royal Navy, built by Francis Baylie in Bristol and launched in June 1674.

On 23 February 1684, Captain John Tyrrell was appointed to command the ship.

From 1701 to 1702 Oxford underwent a Great Repair amounting to rebuilding at Deptford.

[1][3] On 29 June 1723 she was ordered to be taken to pieces at Portsmouth Dockyard, and rebuilt by Joseph Allin the younger to the lines of a 50-gun fourth rate of the 1719 Establishment.

[2] Towards the end of the Seven Years' War the ship was commanded by Mariot Arbuthnot.