HMS Weymouth was a 60-gun fourth rate ship of the line of the Royal Navy, launched in 1736 and in service during the War of the Austrian Succession.

Three of Weymouth's officers were subsequently found guilty of negligence, with two required to pay substantial fines and the third sentenced to a two-year jail term.

She was armed with twenty-four 24-pounder cannons located along her gundeck, supported by 26 nine-pounders on the upper deck and ten 6-pounders ranged along the quarterdeck and the forecastle.

The following year the ship was commanded by Captain Charles Knowles and participated in the Battle of Cartagena de Indias in March 1741.

She put to sea on 18 November 1744 to join a squadron under vice-admiral Thomas Davers, which was escorting a merchant convoy destined for the Caribbean.