The biceps femoris long head is at the most risk for injury, possibly due to its reduced moment of knee and hip flexion as compared to the medial hamstrings.

[2] The muscle group is prone to injuries due to the explosive nature of movement in sports and thus causing overload and overstretching of the hamstring musculature.

The other causes may be: This condition is most commonly seen in: Sensation of cramp or tightness and a slight feeling of pain when the muscles are stretched or contracted.

Within the first five days, the hamstring is rested in an elevated position with an ice pack applied for twenty minutes every two hours.

[7] Women were approximately 3 times more likely to develop hamstring strain than males with the majority of these being non-sporting scenarios.

[9] One explanation is that older active individuals may be at greater risk due to lower levels of eccentric knee flexor strength compared with their younger counterparts.

[11] In another study, that analyzed 25 NCAA sports over four years, it was clearly shown that hamstring strain rates are higher in the preseason.

They must first contract concentrically during the end of the stance phase in order to bend the knee and allow the foot (along with dorsiflexion at the ankle) to clear the ground.

Studies have shown that "the hamstring group reaches peak elongation and acts eccentrically at the hip and knee during the late swing phases of running"[12] and that "the hamstrings are most active and develop the greatest torques at the hip and knee during the late swing through midstance phase of running.

Typical return to play protocols for hamstring strain for sprint demands must include the sprint related activities above progressing to qualities like acceleration, late acceleration, maximum velocity, and speed endurance for effective rehabilitation and preparation for sport demands.

Thus exercises like the Upright-Hip-Extension and Nordic Hamstring Curl without Hip Flexion in isolation will not adequately prepare for sport related activities.