[1] Based on the comparison of a series of monozygotic and dizygotic twins, Freire-Maia (1961) concluded that the preference in the type of hand clasping was affected by certain genetic factors, and (perhaps) to a significant extent.
Hand wringing has been studied in psychology to understand its underlying motivations and implications for mental well-being, of which include nonverbal communication and self-soothing behavior.
The act of hand wringing, along other motor actions, has been observed common in people with Rett syndrome, a genetic brain disorder, for decades.
Hand clasping holds significance in several religious and spiritual practices around the world, often symbolizing different aspects of faith.
While not explicitly addressed in religious texts or practices, individuals may engage in the behavior during moments of spiritual reflection such as prayer or meditation.
In some Christian ceremonies, such as weddings or baptisms, hand clasping may signify the joining of two individuals or families in a sacred bond.
In Mandaeism, the Mandaic term kushta (which also means 'truth') refers to a sacred handclasp that is used during Mandaean rituals such as the masbuta, masiqta, and priestly initiation ceremonies.